Skeletal System Antioxidant Screening Service
The relationship between free radicals and diseases has become a hot spot in the field of modern medicine and life sciences. Many diseases are related to cellular oxidative stress caused by free radicals, and antioxidants can reduce or eliminate free radicals and prevent or reduce the damage of free radical oxidative stress. A large number of anti-free radical drugs or antioxidants have been developed successively, and even free radicals are used as an auxiliary index in disease diagnosis.
Bone is one of the most important tissues of the human body. Oxidative stress injury of bone cells (such as chondrocytes and osteoblasts) is closely related to arthritis and osteonecrosis, which will cause serious pain and burden to patients. Creative Bioarray provides antioxidant rescue evaluating service. Based on the established oxidative stress model of the skeletal system, we can provide anti-ROS drug / antioxidant administration experiments, pharmacy pharmacology, efficacy evaluation, and pharmacokinetic analysis at the same time. The purpose of this service is to promote the screening and development of antioxidants and anti-ROS in the skeletal system.
Service Content
As an expert in the field of cell stress, we can provide customers with a one-stop service. At the same time, our experimental scheme is very flexible, and customers can choose different schemes according to their own needs.
- Scheme I - Model Establishment + Anti-ROS Drug /h Antioxidant Screening Service
The osteogenic stress model was established based on selected chondrogenic cells. We usually use hydrogen peroxide, X / XO, or viruses as the source of oxidative stress. We can choose the source of oxidative stress according to the requirements of customers. Provide anti-ROS drug / antioxidant administration experiment, pharmacy pharmacology, efficacy evaluation, and pharmacokinetic analysis according to customer requirements.
- Scheme II - Anti-ROS Drug / Antioxidant Screening Service
The customer provides established stress cell lines or oxidatively damaged tissues. After culturing cells or tissues, we provide anti-ROS drug / antioxidant administration experiments, pharmacy pharmacology, efficacy evaluation, and pharmacokinetic analysis.
- Scheme III - Anti-ROS Drug / Antioxidant Candidate Evaluating Service
We can evaluate the antioxidant capacity and the ability to rescue oxidative damage of candidate drugs given by customers and provide suggestions for efficacy evaluation and candidate confirmation.
Available Antioxidants
At present, antioxidants with promising applications can be divided into two categories
Enzymatic antioxidants
- Superoxide dismutase, glutathione peroxidase, catalase
Non-enzymatic antioxidants
- Synthetic antioxidants (EMQ, BHT, BHA) vitamin antioxidants (vitamins A, E, C, α- Lipoic acid, β- Carotene, L-carnitine) trace elements, Chinese herbal medicine or plant extracts (polysaccharides, flavonoids, polyphenols, saponins, alkaloids)
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you the first time.
All services and products are for scientific use only, not for medical use！
