Intestinal Epithelial Oxidative Stress Cell Model Construction Service
Intestinal epithelial cells have severe oxidative stress in a variety of physiological, pathological and dietary processes. There are 2 methods to study intestinal epithelial cell injury, including animal model and cell model. Using animal model alone has some disadvantages, such as high cost, instability, difficulty in mechanism research and so on. Therefore, it is very necessary to construct an appropriate cell culture model as a supplement to the animal model. Creative Bioarray has established a complete set of intestinal epithelial cell culture and stress-induced SOP in order to provide customers with the establishment of intestinal epithelial cell stress model. We will provide you with appropriate cell types and induction methods according to the needs of researchers.
Why Establish Intestinal Epithelial Cell Stress Model
- The extensive use of animal tests does not meet the requirements of animal welfare
- The intestinal environment is extremely complex, and the intestinal epithelial cell model is helpful to judge the source of oxidative stress
- Animal model research has high cost and long cycle
- In vivo real-time monitoring technology is not yet mature, and the half-life of free radicals is very short, which is difficult to be monitored in animal models.
- Intestinal cells cultured in vitro have the advantages of good stability, repeatability and low experimental cost
- In vitro cell stress model is helpful to directly study the relationship between intestinal flora and intestinal wall
Our Services
At present, a variety of oxidative stress modeling methods have been developed, and each modeling method has its applicable simulation conditions. The actual research needs to be selected according to the research content of the researcher. The commonly used intestinal epithelial cells include primary cultured cells and passage cells. Primary cultured cells can truly reflect the characteristics of intestinal epithelial cells, but they have the disadvantages of cumbersome operation and long-term use. There are many kinds of subcultured cells, so researchers need to select the species and genera studied.
The methods we commonly use to simulate oxidative stress include physical methods (irradiation, UV irradiation, hypoxia / reoxygenation) and chemical methods (hydrogen peroxide modeling, xanthine / xanthine oxidase modeling). You can click here to view the details of our intestinal epithelial cell modeling methods.
The modeling of intestinal epithelial cells must be inseparable from intestinal epithelial cells. According to the way of obtaining cells, cells cultured in vitro can usually be divided into primary culture cells and subculture cells. You can click here to view the cell lines we provide and our cell culture services.
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you at the first time.
All services and products are for scientific use only, not for medical use！
