Circulatory System Oxidative Stress Modeling Service
There are mainly two kinds of oxidative stress models: animal model and cell model. The cell model has perfect metabolic function and electrophysiological characteristics avoid the interaction between different cells in the whole body, has strong specificity and controllability, and is easy to repeat. Blood vessels and the heart are the core parts of the circulatory system. The cardiovascular system is a sealed pipeline system, and the heart is a muscular power device that pumps blood. In recent years, more and more studies have found that under many pathological conditions, excessive production of oxygen free radicals in myocardial tissue causes excessive accumulation of reactive oxygen species or related substances in myocardial cells, that is, oxidative stress, which further produces various toxic effects on cells, leading to reversible or irreversible damage.
Vascular endothelial cells not only play an important role as a barrier but also release a variety of bioactive substances such as prostacyclin, endothelium-derived relaxing factor, and endothelin, which play an important role in regulating vascular tension and maintaining vascular flow. When endothelial cells are damaged, their barrier function, endocrine function, and anticoagulation process may be damaged, thus becoming the initial link of atherosclerosis.
Creative Bioarray provides our customers with in Vitro oxidative stress modeling services for cardiomyocytes and vascular endothelial cells. Based on these established models, we can simultaneously provide anti-free radical drug / antioxidant administration experiments, pharmacy pharmacology, efficacy evaluation, and pharmacokinetic analysis. The purpose of this service is to promote the screening and development of antioxidants and anti-free radicals in the circulatory system.
The heart is the most important organ in the circulatory system and the main pump of the whole circulatory system of life. Creative Bioarray provides our customers with a variety of services related to oxidative stress in cardiomyocytes including
- Establishment of Myocardial Oxidative Stress Model
- Cardiomyocyte Antioxidant Evaluation Service
- Medicine Cardiac Toxicity Assessment Service
- Gene-Level Stress Assessment of Cardiomyocyte
We have established an in Vitro vascular endothelial cell oxidative damage model for our customers to observe its oxidative damage effect on vascular endothelial cells, and to lay a foundation for further oxidative damage inhibition experiments.
Creative Bioarray provides services for evaluating the protective effect of antioxidants on oxidative damage of vascular endothelial cells in Vitro. Based on the established in Vitro vascular endothelial cell oxidative stress model, we can simultaneously provide antioxidant administration experiments, pharmacy pharmacology, efficacy evaluation, and pharmacokinetic analysis.
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you the first time.
All services and products are for scientific use only, not for medical use！
