Organelle Level Stress Assay
The effects of ROS on cells include oxidative modification of macromolecules, affecting cell survival, proliferation, and aging, also mostly at the molecular level and at the overall cellular level, with less focus on subcellular compartmental changes.
Mild oxidative stress activates the corresponding signaling pathways. In contrast, severe stress causes excessive oxidation of molecules, changes in subcellular compartments, and irreversible cellular damage. To more accurately measure the level of oxidative stress in cells, the level of oxidative stress in the organelles themselves or subcellular compartments is also of great interest. As a leader in cellular stress, Creative Bioarray offers our customers the service of monitoring the level of oxidative stress in organelles themselves or subcellular compartments.
Mitochondria and ROS play an important role in physiological and pathological processes. A variety of methods have been developed to detect mitochondria and ROS. At present, the detection methods of mitochondria include mitochondrial genome sequencing, respiratory control, mitochondrial ATP production rate, membrane potential, and so on. In addition, the morphological and quantitative changes of mitochondria can be directly observed through the electron microscope.
Creative Bioarray provides mitochondrial oxidative stress detection services. Our tests can be performed using a variety of systems, from primary cells to isolated mitochondria, and can be used to demonstrate improved metabolic function or reduce the risk of potential toxins. Our scientists are also experts in designing biochemical-related experimental models to study changes in cell metabolism in the context of cancer, metabolic syndrome, and other diseases with bioenergy challenges.
Creative Bioarray has summarized the activation pathways of ER stress and provides services to assess ER homeostasis and stress accordingly. The results of our assessments can be used by researchers to plan and interpret experiments in vitro and in vivo in mammalian systems, helping to elucidate the relationship between endoplasmic reticulum stress and cellular stress, and even disease.
As leaders in the field of cellular stress, we use probes that can be localized to specific cellular regions and are useful for measuring regional oxidative stress, such as stress in cell membranes.
Creative Bioarray offers our customers a ROS localization service in lipid membranes. Through this service, we can specifically depict for our customers the different oxidative stress states of lipid membranes in response to specific exogenous oxidative stimuli, promising to reveal the detailed mechanisms of intracellular oxidative stress.
Why Select Us
- We have an experienced team of experts, ready to solve your problems
- Professional and high-quality services
- Products have passed strict inspections to ensure the accuracy of research
- Customized one-stop cost-effective technical services
- A variety of services related to cell stress, saving you time and effort
- We provide our customers with comprehensive support
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you the first time.
All services and products are for scientific use only, not for medical use！
