Oxidative stress is a negative effect produced by free radicals in the body, and is considered to be an important factor leading to aging and disease. As far as the ovary is concerned, oxidative stress not only affects the generation of eggs, the development of follicles, the maturation of eggs, the atresia of follicles and ovulation, but also reduces the quality of oocytes and embryos and the development ability of early embryos, which will significantly reduce the fertilization rate, embryo quality and pregnancy rate. As far as the male reproductive system is concerned, oxidative stress damage affects semen quality by affecting sperm concentration, reducing sperm motility, destroying sperm DNA integrity, changing sperm morphology and accelerating sperm apoptosis, and finally leads to infertility.
As a leader in the biotechnology industry, Creative Bioarray provides our customers with the establishment of oxidative stress models of ovary and male reproductive system. We can conduct induction modeling in a variety of ways to make it suitable for various research purposes.
We use the method of intraperitoneal injection of citric acid solution to provide rat ovarian stress modeling for research in related scientific fields and provide a certain basis for clinical research on related mechanisms.
The mouse ovarian stress model is establishes a research platform for further studying the molecular mechanism of oxidative stress and ovarian injury and screening antioxidants.We three stressors for customers to choose from - hydrogen peroxide, 3-nitropropionic acid and sodium arsenite.
The model is established in order to provide reference for the mechanism research and experiment of the effect of oxidative stress on ovarian and reproductive function.
We use human ovarian granulosa cells and H2O2 as inducer to construct an in vitro oxidative stress cell model, and evaluates the model through cell apoptosis and ROS leve.
We hve established a male mouse reproductive system oxidative stress model for its customers by using a variety of oxidative stressors (heavy metal pollutants, cigarette smoke exposure, organic industrial pollutants, lipopolysaccharide, hydroperoxide, endocrine hormone).
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you at the first time.