Skin System Oxidative Stress Modeling Service
The skin is the largest organ of the body. Skin aging is an important component of aging and is associated with oxidative stress, DNA damage and apoptosis. Therefore, prevention and delay of skin aging has become one of the hot topics of life science research. Skin aging consists of two processes, intrinsic aging and photoaging.
Creative Bioarray provides our clients with in vitro oxidative stress modeling services for skin systems.
Available Cell Types
Our available cell types include
- Skin fibroblasts
- Human immortalized melanocyte cell lines
- Melanoma cell lines
Our Common Modeling Tools Include
- H2O2 induction
- Long-wave UV evoked
- 8-MOP/UVA induction
Service Applications
Based on these established models, we can provide simultaneous anti-free radical drug/antioxidant dosing experiments, drug pharmacology, efficacy evaluation and pharmacokinetic analysis.
The purpose of this service is to facilitate the screening and development of antioxidants and anti-free radicals in the skin system.
- Study the mechanism of skin photoaging and the efficacy of anti photoaging substances
- Regulation of stress state in skin fibroblasts
- Laying the foundation for studying the pathogenesis of oxidative stress in skin diseases such as vitiligo
Available Services at Creative Bioarray
We simulated the photoaging environment by UVA or 8-methoxypsoralen combined with UVA. Hydrogen peroxide induced cell senescence through oxidative stress.
Antioxidants can reduce or eliminate free radicals, prevent or reduce the damage of free radical oxidative stress. We provide screening and evaluation services for skin fibroblast antioxidants and anti-aging drugs / components.
We can help our clients to study the role of miRNA in the pathological process of skin photoaging. Help to study the regulatory role of miRNA in long wave ultraviolet (UVA) - induced photoaging model.
We can help our customers to model oxidative stress in melanocytes (immortalized melanocyte line PIG1) and melanoma cells (M14) through H2O2. Laying the foundation for studying the pathogenesis of oxidative stress in skin diseases such as vitiligo
Why Select Us
We have an experienced team of experts, ready to solve your problems
Professional and high-quality services
Products have passed strict inspections to ensure the accuracy of research
Customized one-stop cost-effective technical services
A variety of services related to cell stress, saving you time and effort
We provide our customers with comprehensive support
Creative Bioarray is dedicated to providing high-quality products, comprehensive services, and tailored solutions to support and facilitate life sciences and pharmaceutical research and development. If you have any questions or needs, please contact us, and our customer service staff will help you the first time.
All services and products are for scientific use only, not for medical use！
